Thermo Fisher Scientific’s Olink Platform Selected for World’s Largest Human Proteome Study
Thermo Fisher Scientific (NYSE: TMO) announced that its Olink® Explore Platform has been selected for the UK Biobank Pharma Proteomics Project (UKB-PPP), the world's largest human proteomics study. The project aims to analyze over 5,400 proteins from 600,000 samples to discover new protein biomarkers for disease prediction, diagnosis, and treatment.
The project, a collaboration between UK Biobank and 14 leading biopharmaceutical companies, builds on a 2023 pilot project that analyzed 54,000 samples. The study is scheduled to begin in Q1 2025, with data releases starting in 2026 and full dataset availability in 2027. Initially, the project will analyze 300,000 samples, with plans to secure additional funding for another 300,000 samples.
The pilot study's research, published in Nature, has already been cited over 400 times, demonstrating its significant impact on understanding disease development and advancing targeted treatments. One study identified protein risk factors for certain cancers up to seven years before diagnosis.
Thermo Fisher Scientific (NYSE: TMO) ha annunciato che la sua Piattaforma Olink® Explore è stata selezionata per il Progetto di Proteomica Pharma del UK Biobank (UKB-PPP), il più grande studio di proteomica umana al mondo. L'obiettivo del progetto è analizzare oltre 5.400 proteine da 600.000 campioni per scoprire nuovi biomarcatori proteici per la previsione, diagnosi e trattamento delle malattie.
Il progetto, una collaborazione tra il UK Biobank e 14 importanti aziende biopharma, si basa su un progetto pilota del 2023 che ha analizzato 54.000 campioni. Lo studio è previsto per iniziare nel primo trimestre del 2025, con il rilascio dei dati che inizierà nel 2026 e disponibilità del dataset completo nel 2027. Inizialmente, il progetto analizzerà 300.000 campioni, con piani per garantire finanziamenti aggiuntivi per altri 300.000 campioni.
La ricerca dello studio pilota, pubblicata su Nature, è già stata citata oltre 400 volte, dimostrando il suo impatto significativo sulla comprensione dello sviluppo delle malattie e sull'avanzamento dei trattamenti mirati. Uno studio ha identificato fattori di rischio proteico per alcuni tumori fino a sette anni prima della diagnosi.
Thermo Fisher Scientific (NYSE: TMO) anunció que su Plataforma Olink® Explore ha sido seleccionada para el Proyecto de Proteómica Pharma del UK Biobank (UKB-PPP), el estudio de proteómica humana más grande del mundo. El proyecto tiene como objetivo analizar más de 5,400 proteÃnas de 600,000 muestras para descubrir nuevos biomarcadores proteicos para la predicción, diagnóstico y tratamiento de enfermedades.
El proyecto, una colaboración entre el UK Biobank y 14 importantes compañÃas biofarmacéuticas, se basa en un proyecto piloto de 2023 que analizó 54,000 muestras. El estudio está programado para comenzar en el primer trimestre de 2025, con lanzamientos de datos comenzando en 2026 y disponibilidad completa del conjunto de datos en 2027. Inicialmente, el proyecto analizará 300,000 muestras, con planes de asegurar financiamiento adicional para otras 300,000 muestras.
La investigación del estudio piloto, publicada en Nature, ya ha sido citada más de 400 veces, demostrando su impacto significativo en la comprensión del desarrollo de enfermedades y el avance de tratamientos dirigidos. Un estudio identificó factores de riesgo proteicos para ciertos cánceres hasta siete años antes del diagnóstico.
Thermo Fisher Scientific (NYSE: TMO)는 ìžì‚¬ì˜ Olink® Explore 플랫í¼ì´ 세계ì—ì„œ 가장 í° ì¸ê°„ 단백질 ì—°êµ¬ì¸ UK Biobank ì œì•½ 단백질체 프로ì 트(UKB-PPP)ì— ì„ ì •ë˜ì—ˆë‹¤ê³ 발표했습니다. ì´ í”„ë¡œì íŠ¸ì˜ ëª©í‘œëŠ” 600,000ê°œì˜ ìƒ˜í”Œì—ì„œ 5,400ê°œ ì´ìƒì˜ ë‹¨ë°±ì§ˆì„ ë¶„ì„하여 질병 예측, 진단 ë° ì¹˜ë£Œë¥¼ 위한 새로운 단백질 ë°”ì´ì˜¤ë§ˆì»¤ë¥¼ 발견하는 것입니다.
ì´ í”„ë¡œì 트는 UK Biobank와 14ê°œ 주요 ìƒëª…공학 íšŒì‚¬ì˜ í˜‘ë ¥ìœ¼ë¡œ 진행ë˜ë©°, 2023ë…„ì˜ íŒŒì¼ëŸ¿ 프로ì 트를 바탕으로 í•˜ê³ ìžˆìŠµë‹ˆë‹¤. 해당 프로ì 트는 54,000ê°œì˜ ìƒ˜í”Œì„ ë¶„ì„했습니다. 연구는 2025ë…„ 1ë¶„ê¸°ì— ì‹œìž‘í• ì˜ˆì •ì´ë©°, ë°ì´í„° 공개는 2026년부터 ì‹œìž‘í•˜ê³ ì „ì²´ ë°ì´í„°ì…‹ì€ 2027ë…„ì— ì´ìš© ê°€ëŠ¥í• ì˜ˆì •ìž…ë‹ˆë‹¤. 초기 단계ì—서는 300,000ê°œì˜ ìƒ˜í”Œì„ ë¶„ì„í•˜ê³ , 추가로 300,000ê°œì˜ ìƒ˜í”Œì„ ìœ„í•œ 추가 ìžê¸ˆì„ í™•ë³´í• ê³„íšìž…니다.
파ì¼ëŸ¿ ì—°êµ¬ì˜ ê²°ê³¼ëŠ” Natureì— ë°œí‘œë˜ì—ˆìœ¼ë©°, ì´ë¯¸ 400회 ì´ìƒ ì¸ìš©ë˜ì–´ 질병 발달 ì´í•´ì™€ 목표 치료 ë°œì „ì— ì¤‘ìš”í•œ ì˜í–¥ì„ ë¯¸ì¹˜ê³ ìžˆìŒì„ ë³´ì—¬ì¤ë‹ˆë‹¤. í•œ 연구ì—서는 íŠ¹ì • ì•”ì˜ ë‹¨ë°±ì§ˆ 위험 ì¸ìžë¥¼ 진단 7ë…„ ì „ê¹Œì§€ 확ì¸í–ˆìŠµë‹ˆë‹¤.
Thermo Fisher Scientific (NYSE: TMO) a annoncé que sa Plateforme Olink® Explore a été choisie pour le Projet de Protéomique Pharma du UK Biobank (UKB-PPP), la plus grande étude de protéomique humaine au monde. Le projet vise à analyser plus de 5.400 protéines à partir de 600.000 échantillons pour découvrir de nouveaux biomarqueurs protéiques pour la prédiction, le diagnostic et le traitement des maladies.
Le projet, une collaboration entre UK Biobank et 14 grandes entreprises biopharmaceutiques, s'appuie sur un projet pilote de 2023 qui a analysé 54.000 échantillons. L'étude devrait débuter au premier trimestre de 2025, avec des publications de données commençant en 2026 et disponibilité complète du jeu de données en 2027. Initialement, le projet analysera 300.000 échantillons, avec des plans pour sécuriser un financement supplémentaire pour 300.000 échantillons supplémentaires.
La recherche du projet pilote, publiée dans Nature, a déjà été citée plus de 400 fois, démontrant son impact significatif sur la compréhension du développement des maladies et l'avancement des traitements ciblés. Une étude a identifié des facteurs de risque protéiques pour certains cancers jusqu'à sept ans avant le diagnostic.
Thermo Fisher Scientific (NYSE: TMO) gab bekannt, dass seine Olink® Explore Plattform für das UK Biobank Pharma Proteomics Project (UKB-PPP), die weltweit größte Studie zur menschlichen Proteomik, ausgewählt wurde. Das Projekt hat das Ziel, über 5.400 Proteine aus 600.000 Proben zu analysieren, um neue Proteinbiomarker zur Vorhersage, Diagnose und Behandlung von Krankheiten zu entdecken.
Das Projekt ist eine Zusammenarbeit zwischen dem UK Biobank und 14 führenden biopharmazeutischen Unternehmen und baut auf einem Pilotprojekt aus dem Jahr 2023 auf, das 54.000 Proben analysierte. Die Studie soll im ersten Quartal 2025 beginnen, wobei die Veröffentlichung der Daten 2026 beginnt und der vollständige Datensatz 2027 zur Verfügung steht. Zunächst wird das Projekt 300.000 Proben analysieren, mit dem Plan, zusätzliche Mittel für weitere 300.000 Proben zu sichern.
Die Forschung des Pilotprojekts, veröffentlicht in Nature, wurde bereits über 400 Mal zitiert, was ihren erheblichen Einfluss auf das Verständnis der Krankheitsentwicklung und die Fortschritte bei zielgerichteten Behandlungen verdeutlicht. Eine Studie identifizierte risikobehaftete Proteinmarker für bestimmte Krebsarten bis zu sieben Jahre vor der Diagnose.
- Selected for world's largest proteomics study, strengthening market position
- Project involves analysis of 600,000 samples, indicating significant revenue potential
- Partnership with 14 leading biopharmaceutical companies enhances industry relationships
- Previous pilot study success with 400+ citations demonstrates platform's reliability
- Project start delayed until Q1 2025
- Second phase of 300,000 samples dependent on securing additional funding
Insights
This groundbreaking proteomics study represents a major leap forward in biomedical research. The scale of analyzing 5,400 proteins across 600,000 samples is unprecedented and will create an invaluable dataset for disease research. Previous pilot studies have already demonstrated practical applications, identifying protein signatures for multiple sclerosis and early cancer detection up to seven years before diagnosis.
The collaboration between UK Biobank and 14 pharmaceutical companies significantly amplifies the commercial potential of this research. The staggered data release starting in 2026 will likely accelerate drug discovery pipelines and biomarker development across the industry. For TMO, securing this high-profile project validates their
Think of this as creating a detailed "protein atlas" of human health - similar to how Google Maps revolutionized navigation, this comprehensive protein mapping will transform how we understand and treat diseases.
This contract win strengthens TMO's market position in the high-growth proteomics sector, estimated to reach
The project's massive scale - 600,000 samples over multiple years - provides significant revenue visibility. More importantly, the resulting database will create a network effect, potentially making Olink the de facto standard for proteomics research and increasing switching costs for customers. This strategic positioning could lead to expanded profit margins and market share gains in the broader life sciences tools sector.
The timing of this project is particularly strategic as it coincides with growing industry focus on proteomics-based precision medicine. With over 19,000 researchers already using UK Biobank data, the addition of comprehensive proteomics data will likely spark a wave of new research initiatives, driving demand for TMO's instruments and consumables.
The involvement of 14 major pharmaceutical companies indicates strong commercial interest in proteomics-based drug discovery. This project effectively positions TMO to capture a larger share of pharma R&D budgets, estimated at
“Studies on the human proteome are having a profound impact on our customers’ fundamental understanding of disease and the advancement of life sciences research,†said Marc N. Casper, chairman, president and chief executive officer of Thermo Fisher. “The unprecedented scale of this project, with support from our next-generation proteomics solution, underscores the potential to deepen their knowledge and develop new applications to improve human health.â€
Advancement of the Olink Explore Platform, which is designed to enable deep analysis of the thousands of proteins in the human body, provides researchers with the ability to study the role they play in many types of diseases. Published studies in this emerging field, known as population proteomics, have demonstrated the potential protein signatures have to help advance the future of precision medicine.
“Proteomics provides an incredibly detailed snapshot of health. This new frontier of science can unveil how genetics and external factors – like diet, exercise and climate – interact, and will help to pinpoint the key causes of diseases and identify drug targets,†said Professor Naomi Allen, chief scientist of
UKB-PPP is a collaboration between
“UKB-PPP brings together scientists from the world’s leading pharmaceutical companies with the most advanced research technologies,†said Chris Whelan, Ph.D., chair and principal investigator of UKB-PPP. “Success for projects of this size depends on having partners with the ability to scale reliably and effectively. We are excited to once again have Thermo Fisher’s Olink platform as the supporting proteomics technology to drive this study.â€
UKB-PPP builds on the findings released in 2023 from the pilot project, which also leveraged the Olink Explore platform to analyze more than 54,000 samples from
UKB-PPP is scheduled to begin in Q1 2025, with plans to make the proteomic data available to
Acquired by Thermo Fisher in July 2024, the Olink proteomics platform is a next generation proteomics solution that empowers researchers to measure more than 5,400 proteins with high specificity, speed, and the flexibility to study complex biological processes.
To learn more about the Olink Platform, please visit
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue over
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