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Predictive Oncology Announces Agreement to be Acquired by Renovaro

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Predictive Oncology (NASDAQ: POAI) has entered into a binding letter of intent to be acquired by Renovaro (NASDAQ: RENB). The merger combines complementary AI/ML platforms to enhance cancer drug discovery and patient outcomes. Under the agreement, POAI shareholders will receive preferred Renovaro stock in a 1:1 exchange, automatically redeemable for $3.00 per share after 18 months.

The deal promises over 30% reduction in combined operating expenses and leverages POAI's biobank of 150,000+ patient tumor samples with Renovaro's multi-omic AI expertise. The merger requires minimum fundraising of $15 million by Renovaro and shareholder approval by February 28, 2025. If POAI's Series A and B warrant holders don't exercise by January 15, 2025, Renovaro will purchase up to 2.33 million POAI shares at $1.07 per share.

Predictive Oncology (NASDAQ: POAI) ha firmato una lettera di intenti vincolante per essere acquisita da Renovaro (NASDAQ: RENB). La fusione unisce piattaforme AI/ML complementari per migliorare la scoperta di farmaci per il cancro e i risultati per i pazienti. In base all'accordo, gli azionisti di POAI riceveranno azioni privilegiate di Renovaro in un rapporto 1:1, riscattabili automaticamente per $3.00 per azione dopo 18 mesi.

Il contratto promette oltre il 30% di riduzione delle spese operative combinate e capitalizza la biobanca di POAI con oltre 150.000 campioni tumorali di pazienti insieme all'esperienza multi-omica di AI di Renovaro. La fusione richiede un finanziamento minimo di $15 milioni da parte di Renovaro e l'approvazione degli azionisti entro il 28 febbraio 2025. Se i titolari dei warrant di Serie A e B di POAI non esercitano il loro diritto entro il 15 gennaio 2025, Renovaro acquister脿 fino a 2,33 milioni di azioni di POAI a $1.07 per azione.

Predictive Oncology (NASDAQ: POAI) ha firmado una carta de intenci贸n vinculante para ser adquirida por Renovaro (NASDAQ: RENB). La fusi贸n combina plataformas complementarias de IA/ML para mejorar el descubrimiento de medicamentos contra el c谩ncer y los resultados de los pacientes. Seg煤n el acuerdo, los accionistas de POAI recibir谩n acciones preferentes de Renovaro en un intercambio 1:1, canjeables autom谩ticamente por $3.00 por acci贸n despu茅s de 18 meses.

El acuerdo promete una reducci贸n de m谩s del 30% en los gastos operativos combinados y aprovecha el biobanco de POAI con m谩s de 150,000 muestras tumorales de pacientes junto con la experiencia en IA multi-贸mica de Renovaro. La fusi贸n requiere una recaudaci贸n m铆nima de $15 millones por parte de Renovaro y la aprobaci贸n de los accionistas antes del 28 de febrero de 2025. Si los tenedores de warrants de las Series A y B de POAI no ejercen su derecho antes del 15 de enero de 2025, Renovaro comprar谩 hasta 2.33 millones de acciones de POAI a $1.07 por acci贸n.

Predictive Oncology (NASDAQ: POAI)Renovaro (NASDAQ: RENB)鞐 鞚胳垬霅橁赴 鞙勴暅 甑啀霠 鞛埖鐢 鞚橃偓 瓿勳暯靹滌棎 靹滊獏頄堨姷雼堧嫟. 鞚措矆 鞚胳垬頃╇硲鞚 鞎 鞎诫 氚滉铂 氚 頇橃瀽 旃橂 瓴瓣臣 頄レ儊鞚 鞙勴暣 靸來樃 氤挫檮鞝侅澑 AI/ML 頂岆灚韽检潉 韱淀暕頃╇媹雼. 氤 瓿勳暯鞐 霐半澕 POAI 欤检<霌れ潃 1:1 牍勳湪搿 Renovaro鞚 鞖办劆欤茧ゼ 氚涭溂氅, 18臧滌洈 頉勳棎 鞛愲彊鞙茧 欤茧嫻 $3.00搿 頇橂秷霅╇媹雼.

鞚措矆 瓿勳暯鞚 韱淀暕 鞖挫榿牍勲ゼ 30% 鞚挫儊 鞝堦皭頃 瓴冹潉 鞎届啀頃橂┌, POAI鞚 150,000臧 鞚挫儊鞚 頇橃瀽 膦呾枒 靸橅攲 氚旍澊鞓る眳韥檧 Renovaro鞚 雼れ 鞓る鞀 AI 鞝勲靹膘潉 頇滌毄頃╇媹雼. 鞚措矆 鞚胳垬頃╇硲鞚 Renovaro鞐愳劀 斓滌唽 1500毵 雼煬鞚 鞛愱笀鞚 氇頃挫暭 頃橂┌, 2025雲 2鞗 28鞚缄箤歆 欤检< 鞀轨澑鞚 頃勳殧頃╇媹雼. 毵岇暯 POAI鞚 A 氚 B 鞁滊Μ歃 鞗岆煱韸 氤挫湢鞛愲摛鞚 2025雲 1鞗 15鞚缄箤歆 甓岆Μ毳 頄夓偓頃橃 鞎姷鐢雼る┐, Renovaro电 POAI鞚 斓滊寑 233毵 欤茧ゼ 欤茧嫻 $1.07鞐 甑Г頃 瓴冹瀰雼堧嫟.

Predictive Oncology (NASDAQ: POAI) a sign茅 une lettre d'intention contraignante pour 锚tre acquise par Renovaro (NASDAQ: RENB). La fusion combine des plateformes AI/ML compl茅mentaires afin d'am茅liorer la d茅couverte de m茅dicaments contre le cancer et les r茅sultats pour les patients. En vertu de l'accord, les actionnaires de POAI recevront des actions privil茅gi茅es de Renovaro dans un rapport de 1:1, 茅changeables automatiquement pour 3,00 $ par action apr猫s 18 mois.

L'accord promet une r茅duction de plus de 30 % des d茅penses d'exploitation combin茅es et tire parti de la biobanque de POAI avec plus de 150 000 茅chantillons de tumeurs de patients, ainsi que de l'expertise en IA multi-omique de Renovaro. La fusion n茅cessite un financement minimum de 15 millions de dollars de la part de Renovaro et l'approbation des actionnaires d'ici le 28 f茅vrier 2025. Si les d茅tenteurs de bons de souscription de s茅rie A et B de POAI n'exercent pas leur droit d'ici le 15 janvier 2025, Renovaro ach猫tera jusqu'脿 2,33 millions d'actions POAI 脿 1,07 $ par action.

Predictive Oncology (NASDAQ: POAI) hat einen verbindlichen Letter of Intent unterzeichnet, um von Renovaro (NASDAQ: RENB) 眉bernommen zu werden. Die Fusion kombiniert komplement盲re KI/ML-Plattformen, um die Entdeckung von Krebsmedikamenten und die Ergebnisse f眉r Patienten zu verbessern. Laut Vereinbarung erhalten die POAI-Aktion盲re Vorzugsaktien von Renovaro im Verh盲ltnis 1:1, die nach 18 Monaten automatisch zum Preis von 3,00 $ pro Aktie einl枚sbar sind.

Der Deal verspricht eine Reduzierung der kombinierten Betriebskosten um 眉ber 30 % und nutzt die Biobank von POAI mit mehr als 150.000 Patiententumorproben sowie die multi-omische KI-Expertise von Renovaro. Die Fusion erfordert eine Mindestmittelbeschaffung von 15 Millionen US-Dollar durch Renovaro und die Zustimmung der Aktion盲re bis zum 28. Februar 2025. Wenn die Inhaber der Series A und B Warrants von POAI bis zum 15. Januar 2025 kein Recht aus眉ben, wird Renovaro bis zu 2,33 Millionen POAI-Aktien zu je 1,07 $ pro Aktie erwerben.

Positive
  • 30% reduction in combined operating expenses expected
  • Guaranteed $3.00 per share redemption value after 18 months
  • Potential share conversion at 1:1 ratio when Renovaro stock trades above $4.50 for 30 days
  • Renovaro commits to purchase 2.33M shares at $1.07 if warrants aren't exercised
Negative
  • Transaction requires minimum $15M fundraising by Renovaro
  • Deal completion dependent on shareholder approval
  • Risk of receiving only licensing rights if shareholder approval fails

Insights

<p>This merger represents a strategic consolidation in the AI-driven oncology space. The deal structure is particularly noteworthy - <money>$3.00</money> per share redemption value after 18 months provides a significant premium over POAI's current market price, while the 1:1 conversion ratio with <money>$4.50</money> price trigger offers additional upside potential. The <money>$15M</money> minimum fundraising requirement and 30% cost reduction target suggest strong focus on operational efficiency. The backup warrant exercise provision at <money>$1.07</money> per share creates a price floor mechanism.</p>

<p>The combination of POAI's extensive biobank (<b>150,000+ tumor samples</b> and <b>200,000+ pathology slides</b>) with Renovaro's multi-omic AI capabilities creates a formidable platform for accelerated drug discovery. The merged entity's ability to leverage complementary AI/ML technologies while accessing longitudinal drug response data positions it uniquely in the precision oncology space. The fallback provision granting Renovaro exclusive access to POAI's biobank ensures value preservation even if shareholders reject the deal.</p>

<p>The merger's technical synergy is compelling - combining POAI's drug discovery AI platform and rich historical dataset with Renovaro's multi-modal AI capabilities creates a comprehensive solution spanning diagnosis, biomarker discovery and treatment optimization. This integrated approach could significantly reduce drug development timelines and costs while improving success rates. The combined AI infrastructure will benefit from enhanced pattern recognition capabilities across broader datasets, potentially leading to novel therapeutic insights.</p>

- Combination creates immediate scientific synergies by harnessing complementary AI / ML platforms to improve patient outcomes across multiple cancer indications 鈥

- Deal terms align shareholders鈥 interest, augment business development opportunities and positioning in the capital markets -

PITTSBURGH, Jan. 06, 2025 (GLOBE NEWSWIRE) -- Predictive Oncology Inc. (NASDAQ: POAI), a leader in AI-driven drug discovery, today announced that it has entered into a binding letter of intent with Renovaro, Inc. (NASDAQ: RENB) (鈥淩enovaro鈥) for Predictive Oncology to be acquired by Renovaro in exchange for preferred stock of Renovaro.

Predictive and Renovaro share an unwavering commitment to improving outcomes of cancer patients through earlier diagnosis, biomarker discovery and targeted therapies. Further, the companies have proprietary AI / ML platforms with complementary technical advantages that will be leveraged together to accelerate drug discovery and reduce the risk of drug development. Beyond the scientific synergies, the merger presents an opportunity to recognize significant cost savings by reducing operating expenses by more than 30% on a combined basis in the near term.

鈥淪ince we initiated our formal review of strategic alternatives in mid-November, we have received significant inbound interest that has led to ongoing discussions and due diligence with several parties,鈥 stated Raymond Vennare, Chairman and Chief Executive Officer of Predictive Oncology. 鈥淭hrough our discussions with Renovaro, we became increasingly compelled by the strategic potential of combining the Predictive鈥檚 AI-driven drug discovery platform and vast biobank of more than 150,000 patient tumor samples, 200,000 pathology slides and decades of longitudinal drug response data with Renovaro鈥檚 multi-disciplinary artificial intelligence, multi-omic and multi-modal data expertise.鈥

Under the terms of the binding letter of intent, Predictive Oncology will be merged into Renovaro in exchange for a newly created series of preferred stock of Renovaro. The preferred stock will be issued to shareholders of Predictive Oncology in a 1:1 exchange for their existing Predictive Oncology common stock. The preferred stock is automatically redeemable for $3.00 per share after 18 months and may also be converted to freely tradeable, registered Renovaro common stock at a 1:1 conversion ratio by either the holders thereof or Renovaro at any time after Renovaro鈥檚 common stock has traded at or above $4.50 per share for 30 consecutive trading days. Renovaro also has the right to redeem the preferred stock for cash at a redemption price of $3.00 per share (i) if the trading price of its common stock is $3.00 or less or (ii) such preferred stock has not been converted within 30 days after the first date on which the holder could request such conversion as described above. Notwithstanding the foregoing, if holders of Predictive Oncology鈥檚 Series A and Series B warrants do not exercise their warrants before January 15, 2025, Renovaro has agreed to purchase up to 2.33 million shares of Predictive Oncology鈥檚 common stock at $1.07 per share. The parties have agreed to enter into definitive documentation for the merger by no later than February 28, 2025. The merger is subject to a minimum fundraising of $15 million by Renovaro, as well as formal approval by the shareholders of Predictive Oncology. A failure to obtain shareholder approval, assuming prior funding by Renovaro, will entitle Renovaro to a two-year exclusive royalty-free license to Predictive Oncology鈥檚 biobank of tumor samples and tumor-specific 3D cell culture models.

David Weinstein, CEO of Renovaro, stated 鈥淪ince my arrival just two months ago, the management team has been executing on its 100-day plan of action and evaluating strategic opportunities for both of our verticals, RenovaroBio and RenovaroCube. This transaction with Predictive Oncology furthers our quest to offer cancer patients early diagnosis, a personalized treatment protocols, and recurrence monitoring.鈥

Messrs. Weinstein and Vennare continued, 鈥淥ver the coming weeks, we will work diligently to finalize the composition of our leadership team and Board of Directors, as well as details concerning the combined company鈥檚 R&D priorities and operations. We are both fully committed to completing this transaction as soon as possible, and actualizing a new, best-in-class oncology-focused technology that promises patients a brighter future.鈥

There can be no assurance that an agreement or transaction with Renovaro will be executed, or as to the timing of any such agreement or transaction. Predictive Oncology does not intend to discuss or disclose further developments regarding these discussions unless and until its Board of Directors has approved a transaction or otherwise determined that further disclosure is appropriate or required by law.

About Renovaro

Renovaro aims to accelerate precision and personalized medicine for longevity powered by mutually reinforcing AI and biotechnology platforms for early diagnosis, better-targeted treatments, and drug discovery. Renovaro Inc. includes RenovaroBio, an advanced cell-gene immunotherapy company, and Renovaro Cube.

Renovaro Cube has developed an award-winning AI platform that is committed to the early detection of cancer and its recurrence and monitoring subsequent treatments. Renovaro Cube intervenes at a stage where potential therapy can be most effective. Renovaro Cube is a molecular data science company with a background in FinTech and a 12-year history. It brings together proprietary artificial intelligence (AI) technology, multi-omics, multi-modal data, and the expertise of a carefully selected multidisciplinary team to radically accelerate precision medicine and enable breakthrough changes in disease agnostic decision support.

About Predictive Oncology

Predictive Oncology is on the cutting edge of the rapidly growing use of artificial intelligence and machine learning to expedite early biomarker and drug discovery and enable drug development for the benefit of cancer patients worldwide. The company鈥檚 proprietary AI/ML platform has been scientifically validated to predict with 92% accuracy if a tumor sample will respond to a certain drug compound, allowing for a more informed selection of drug/tumor type combinations for subsequent in-vitro testing. Together with the company鈥檚 vast biobank of more than 150,000 assay-capable heterogenous human tumor samples, Predictive Oncology offers its academic and industry partners one of the industry鈥檚 broadest AI-based drug discovery solutions, further complimented by its wholly owned CLIA lab and GMP facilities. Predictive Oncology is headquartered in Pittsburgh, PA.

Contact:
Tim McCarthy
LifeSci Advisors, LLC

Forward-Looking Statements:
Certain matters discussed in this release contain forward-looking statements. These forward- looking statements reflect our current expectations and projections about future events and are subject to substantial risks, uncertainties and assumptions about our operations and the investments we make. All statements, other than statements of historical facts, included in this press release regarding our strategy, future operations, future financial position, future revenue and financial performance, projected costs, prospects, changes in management, plans and objectives of management are forward-looking statements. The words 鈥渁nticipate,鈥 鈥渂elieve,鈥 鈥渆stimate,鈥 鈥渆xpect,鈥 鈥渋ntend,鈥 鈥渕ay,鈥 鈥減lan,鈥 鈥渨ould,鈥 鈥渢arget鈥 and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Our actual future performance may materially differ from that contemplated by the forward-looking statements as a result of a variety of factors including, among other things, factors discussed under the heading 鈥淩isk Factors鈥 in our filings with the SEC. Except as expressly required by law, the company disclaims any intent or obligation to update these forward-looking statements.

This press release was published by a CLEAR庐 Verified individual.


FAQ

What is the exchange ratio for POAI shareholders in the Renovaro acquisition?

POAI shareholders will receive preferred Renovaro stock in a 1:1 exchange ratio for their existing POAI common stock.

When can POAI shareholders redeem their preferred shares for $3.00?

The preferred shares are automatically redeemable for $3.00 per share after 18 months from the merger completion.

What happens if POAI shareholders don't approve the Renovaro merger?

If shareholders don't approve the merger, Renovaro will receive a two-year exclusive royalty-free license to POAI's biobank and tumor-specific 3D cell culture models.

What cost savings are expected from the POAI-Renovaro merger?

The merger is expected to reduce operating expenses by more than 30% on a combined basis in the near term.

What is the deadline for POAI warrant holders to exercise their warrants?

Series A and Series B warrant holders must exercise their warrants before January 15, 2025.

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