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Eterna Therapeutics Inc. (Nasdaq: ERNA) is a leading biopharmaceutical company focused on developing transformational new medicines through advanced mRNA cell engineering technologies. The company's core mission is to harness these technologies to repair cellular dysfunction and address a diverse range of therapeutic indications.
As a pioneer in the field, Eterna is actively engaged in creating groundbreaking mRNA-based therapies aimed at improving patient health outcomes, particularly for those with high unmet medical needs. The company’s extensive portfolio includes over 130 in-licensed patents that cover critical technologies such as mRNA cell reprogramming, mRNA gene editing, and unique delivery systems like the °Õ´Ç¸é±·´¡»å´Çâ„¢ mRNA delivery system, in collaboration with Factor Bioscience.
Eterna's most advanced program includes multiple next-generation therapies in the preclinical stage, targeting conditions like acute respiratory distress syndrome, solid tumors, and rare genetic diseases through in vivo gene-editing therapies. The company's flagship product, IRX-2, a human cell-derived cytokine therapy, has shown promising results in clinical trials for head and neck cancer and is currently advancing through Phase 2b trials.
In recent financial developments, Eterna has successfully closed private placement transactions to raise over $9.2 million, which will support its innovative research and development projects. These transactions involve senior convertible promissory notes and accompanying warrants, reflecting investor confidence in the company's future potential.
The leadership team at Eterna has also seen strategic changes, with the recent appointment of Sanjeev Luther as President and CEO, effective January 1, 2024. Mr. Luther brings extensive experience from his previous roles in global pharmaceutical companies, which will be instrumental in driving Eterna's growth and clinical advancements.
Eterna Therapeutics Inc. will present at the ASGCT 27th Annual Meeting on the development of a beta 2 microglobulin-knockout (B2M-KO) iMSC line with enhanced immunosuppressive activity and stealthing features, potentially improving the therapeutic potential of MSCs in treating inflammatory diseases. The presentation aims to address challenges such as variability in therapeutic responses and in vivo persistence of MSCs, offering promising solutions for autoimmune and inflammatory indications.